2009-11-17 17:18:39 -

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Primary biliary cirrhosis is a disorder of the liver that leads to irreversible liver damage. In this disorder, the bile ducts which transport bile out of the liver, become inflamed and damaged. They block the flow of bile out of the liver. As this disease progresses, the liver cannot function normally. Eventually, complications from liver failure may occur. This form of cirrhosis is more common in women than men.

Causes of Primary Biliary Cirrhosis


Primary biliary cirrhosis is an autoimmune disease in which the bile ducts become inflamed. This leads to blockage of the bile ducts which leads to damage of the liver tissue.

Signs and Symptoms of Primary Biliary Cirrhosis


There may be few or no symptoms during the early stages of cirrhosis.

Loss of appetite and loss of weight may occur. Nausea is common as is jaundice - yellowing of the skin and eyes. Vomiting blood and black, tarry stools may occur. There may be swelling of the abdomen. Bleeding and easy bruising may also occur.

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