2009-11-07 18:03:09 -
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Acute idiopathic thrombocytopenic purpura (ITP) usually follows recovery from a viral disease. It occurs most often in children. About 90% of individuals will show a complete recovery within 3-6 months. Acute ITP is rare in adults. It may be misinterpreted as acute leukemia or aplastic anemia. Adults usually develop chronic ITP. It occurs most commonly in males between the age
of 20 and 40.
Causes of Idiopathic Thrombocytopenia Purpura
Acute ITP is thought to be immunological. In this condition, immune complexes containing viral antigens are found that cross-react with platelets. Chronic ITP is an autoimmune disorder that targets certain components of the cell wall of the platelet.
Signs and Symptoms of Idiopathic Thrombocytopenia Purpura
ITP can be divided into two different forms.
* Acute ITP starts suddenly and usually follows a viral illness in a child. Acute ITP may require no treatment, especially if the platelet count does not fall too low and there is little bleeding. It usually improves spontaneously and, in children at least, rarely comes back.
* Chronic ITP develops over time, is long lasting and more common in adults. It may not need treatment if the platelet level doesn't pose a significant risk of bleeding. Any such assessment should take account of your lifestyle, such as participation in contact sports or manual work.
The hallmarks of ITP include excessive bleeding and easy bruising. In women, heavy menstrual bleeding may occur. Symptoms of anemia may occur, typified by shortness of breath, fatigue, and rapid heart rate.
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