2009-11-06 15:31:06 -

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Histoplasmosis is a fungal infection that is usually spread by inhaling the spores of the fungus, Histoplasma capsulatum. In the U.S., the disease is most prevalent in the Mississippi and Ohio river valleys. The disease may frequently go undiagnosed and undetected. There are four clinical forms of the disease.

Causes of Histoplasmosis


This disorder is due to the fungus, Histoplasma capsulatum. People

become infected by breathing dust that contains fungus spores. These spores most often are found in soil contaminated by feces of birds and bats. Contaminated soil is frequently found in pigeon lofts, barns, chicken houses, and in damp areas under bridges, along streams and in caves.

Signs and Symptoms of Histoplasmosis


Infections with Histoplasmosis may produce little or not symptoms. The mildest form of the disease may produce, mild fever cough and generalized weakness. The second form of the disease occurs when the fungus gains access to the bloodstream and spreads to other areas. There are lumps in neck, armpit or groin. Often, there are ulcers in the gastrointestinal tract or mouth. The chronic form of the disease is similar to tuberculosis. There is shortness of breath and cough. Widespread, or disseminated, Histoplasmosis can occur when the body's defense system, or immune system, is compromised. This can occur in people with cancer, chronic infections or AIDS. Chronic, widespread and pulmonary disease can lead to loss of appetite, diarrhea ,weight loss and fever.

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