The 'Hollywoodland' actor recently underwent the medical procedure - which involves having warm water pumped into the intestines to flush out all un-passed excrement - but admits it was an experience he will not be repeating.
He told Britain's Zoo magazine: 'I lost my virginity all over again that day, in so many ways. I don't think I will be having it done again.' Colonic irrigation is not the only health conscious decision Ben has made recently - he has also given up smoking.
The 34-year-old actor revealed it was his role as chain-smoking bondsman Jack Dupree in new movie 'Smokin' Aces' that convinced him to quit.
Ben - who has a one-year-old daughter Violet with his wife Jennifer Garner - said: 'The whole week that I shot, I smoked, like, five packs a day. By the time the movie was over, I was so sick of smoking, I just didn't want to do it anymore, and I quit. But it's pretty cool that I have this celluloid record of the last time I smoked.'