2012-11-27 08:19:31 -

According to a published Bloomberg First Word survey, which sought the opinions
of physicians and four analysts, the medullary thyroid cancer candidate
Cabozantinib from Exelixis, Inc. (NASDAQ: EXEL) which faces an FDA PDUFA
decision date on November 29th is likely to get approved.

Formerly known as XL184, Cabozantinib, is said to work by blocking signaling
that leads to cancer growth as well as blocking the growth of new blood vessels
(angiogenesis) that help to feed a tumor. After approval, the drug could be used
"off-label" to treat other cancers.

Analysts from four large firms who have been following the story list the odds
for Cabozantinib's approval as follows:

  * Lazard at 75 percent to 85 percent
  * Piper Jaffray at 80 percent
  * Jefferies at 80   percent, and
  * Cowen at 70 percent

Published reports have Holtorf Medical Group's Dr. Kent Holtorf stating that the
clinical data looked "very reassuring" and more promising for patients than any
other alternatives. He notes that it will be exciting for physician's, which
will now be able to offer something to patients upon approval.

While Piper Jaffray's Ed Tenthoff warns that investors might try to sell the
news following the FDA decision this week, Lazard's Biren Amin sees Exelixis at
$6 to $7 upon approval, or $4 to $5 if rejected.

Exelixis shares traded mostly sideways during today's mixed market, but have
seen a surge in recent weeks leading up to this decision.

Disclosure: None

The full report about how traders are bracing for the upcoming decision is
available at:

 www.biomedreports.com/20121126114161/exelixis-traders-brace-for- ..
fda-decision.html

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new complete database of clinical trials and upcoming FDA and world-wide
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